Op-brai140036 1..10
نویسندگان
چکیده
1 Centre de Recherche, Institut Universitaire de Gériatrie de Montréal, QC, Canada 2 Centre d’Études Avancées en Médicine du Sommeil, Hôpital du Sacré-Cœur de Montréal, QC, Canada 3 Department of Radiology, Faculty of Medicine, University of Montreal, QC, Canada 4 Movement Disorders Unit, McGill University Health Centre, Montréal, QC, Canada 5 Unité des Troubles du Mouvement André Barbeau, Centre Hospitalier de l’Université de Montréal, QC, Canada 6 Department of Psychology, Université du Québec à Montréal, Montréal, QC, Canada
منابع مشابه
Total absence of colony-stimulating factor 1 in the macrophage-deficient osteopetrotic (op/op) mouse.
Osteopetrotic (op/op) mutant mice suffer from congenital osteopetrosis due to a severe deficiency of osteoclasts. Furthermore, the total number of mononuclear phagocytes is extremely low in affected mice. Serum, 11 tissues, and different cell and organ conditioned media from op/op mice were shown to be devoid of biologically active colony-stimulating factor 1 (CSF-1), whereas all of these prepa...
متن کاملOpposite Categories and Contravariant Functors
The opposite category of a category, contravariant functors and duality functors are defined. Next we state the proposition (1) the objects of C, the morphisms of C, the cod-map of C, the dom-map of C, (the composition of C),the id-map of C is a category. Let us consider C. The functor C op yielding a strict category is defined by the condition (Def. 1). (Def. 1) C op = the objects of C, the mo...
متن کاملCSF-1 deficiency in mice results in abnormal brain development.
Colony stimulating factor-1 (CSF-1) was initially identified as a growth factor for mononuclear phagocytes. This study examines the role of CSF-1 in the development of the central nervous system (CNS). CSF-1 treatment of neurons cultured from embryonic brain promoted survival and process outgrowth in a dose-dependent manner. By contrast, CSF-1 treatment of neurons cultured from the osteopetroti...
متن کاملSpleen serves as a reservoir of osteoclast precursors through vitamin D-induced IL-34 expression in osteopetrotic op/op mice.
Osteoclasts are generated from monocyte/macrophage-lineage precursors in response to colony-stimulating factor 1 (CSF-1) and receptor activator of nuclear factor-κB ligand (RANKL). CSF-1-mutated CSF-1(op/op) mice as well as RANKL(-/-) mice exhibit osteopetrosis (OP) caused by osteoclast deficiency. We previously identified RANKL receptor (RANK)/CSF-1 receptor (CSF-1R) double-positive cells as o...
متن کاملDelayed hematopoietic development in osteopetrotic (op/op) mice
Changes in structure, cellularity, hematopoietic progenitor cell and macrophage content, and osteoclast activity were investigated in the hematopoietic organs of the colony-stimulating factor 1(CSF-1)-less osteopetrotic (op/op) mouse. The data indicated that op/op mice undergo an age-related hematopoietic recovery and resolution of osteopetrosis, suggesting that the hematopoietic system has the...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2014